(1 reference)-
- 抗原 See all EIF3A 抗体
- EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))
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抗原表位
- AA 1-250
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EIF3A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 序列
- MPAYFQRPEN ALKRANEFLE VGKKQPALDV LYDVMKSKKH RTWQKIHEPI MLKYLELCVD LRKSHLAKEG LYQYKNICQQ VNIKSLEDVV RAYLKMAEEK TEAAKEESQQ MVLDIEDLDN IQTPESVLLS AVSGEDTQDR TDRLLLTPWV KFLWESYRQC LDLLRNNSRV ERLYHDIAQQ AFKFCLQYTR KAEFRKLCDN LRMHLSQIQR HHNQSTAINL NNPESQSMHL ETRLVQLDSA ISMELWQEAF
- 交叉反应
- 人, 小鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human EIF3A (NP_003741.1).
- 亚型
- IgG
- Top Product
- Discover our top product EIF3A Primary Antibody
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anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) antibody
EIF3A 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (AA 1288-1379) antibodyEIF3A 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (AA 1-75) antibodyEIF3A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (AA 1-75) antibodyEIF3A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G4 unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (C-Term) antibodyEIF3A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (AA 550-600) antibodyEIF3A 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (C-Term) antibodyEIF3A 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (AA 1219-1247), (C-Term) antibodyEIF3A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32052 unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (C-Term) antibodyEIF3A 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 斑马鱼, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) (AA 172-202), (C-Term) antibodyEIF3A 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:1000,IF,1:50 - 1:100
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Picornavirus 2A protease regulates stress granule formation to facilitate viral translation." in: PLoS pathogens, Vol. 14, Issue 2, pp. e1006901, (2018) (PubMed).
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: "Picornavirus 2A protease regulates stress granule formation to facilitate viral translation." in: PLoS pathogens, Vol. 14, Issue 2, pp. e1006901, (2018) (PubMed).
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- 抗原
- EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))
- 别名
- EIF3A (EIF3A 产品)
- 背景
- RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632, PubMed:11169732). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773, PubMed:27462815).,EIF3A,EIF3,EIF3S10,P167,TIF32,eIF3-p170,eIF3-theta,p180,p185,Epigenetics & Nuclear Signaling,RNA Binding,Translation Control,EIF3A
- 分子量
- 162 kDa/166 kDa
- 基因ID
- 8661
- UniProt
- Q14152
- 途径
- Ribonucleoprotein Complex Subunit Organization
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