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EIF3A 抗体 (AA 1-250)

EIF3A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1679692
发货至: 中国
  • 抗原 See all EIF3A 抗体
    EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))
    抗原表位
    • 10
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-250
    适用
    • 41
    • 19
    • 14
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 39
    • 3
    克隆类型
    • 40
    • 2
    多克隆
    标记
    • 21
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EIF3A antibody is un-conjugated
    应用范围
    • 30
    • 20
    • 19
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    MPAYFQRPEN ALKRANEFLE VGKKQPALDV LYDVMKSKKH RTWQKIHEPI MLKYLELCVD LRKSHLAKEG LYQYKNICQQ VNIKSLEDVV RAYLKMAEEK TEAAKEESQQ MVLDIEDLDN IQTPESVLLS AVSGEDTQDR TDRLLLTPWV KFLWESYRQC LDLLRNNSRV ERLYHDIAQQ AFKFCLQYTR KAEFRKLCDN LRMHLSQIQR HHNQSTAINL NNPESQSMHL ETRLVQLDSA ISMELWQEAF
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human EIF3A (NP_003741.1).
    亚型
    IgG
    Top Product
    Discover our top product EIF3A Primary Antibody
  • 应用备注
    WB,1:500 - 1:1000,IF,1:50 - 1:100
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Yang, Hu, Fan, Zhang, Zhong, Guo, Qin, Chen: "Picornavirus 2A protease regulates stress granule formation to facilitate viral translation." in: PLoS pathogens, Vol. 14, Issue 2, pp. e1006901, (2018) (PubMed).

  • 抗原
    EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))
    别名
    EIF3A (EIF3A 产品)
    别名
    EIF3 antibody, EIF3S10 antibody, P167 antibody, TIF32 antibody, eIF3-p170 antibody, eIF3-theta antibody, p180 antibody, p185 antibody, EIF6 antibody, A830012B05Rik antibody, Csma antibody, Eif3 antibody, Eif3s10 antibody, mKIAA0139 antibody, ZH12 antibody, eif3s10 antibody, eIF3 p110 antibody, eIF3a antibody, eukaryotic translation initiation factor 3 subunit A antibody, eukaryotic translation initiation factor 3, subunit A antibody, eukaryotic translation initiation factor 3 subunit A S homeolog antibody, translation initiation factor eIF3a antibody, EIF3A antibody, Eif3a antibody, eif3a.S antibody, tif32 antibody
    背景
    RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632, PubMed:11169732). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773, PubMed:27462815).,EIF3A,EIF3,EIF3S10,P167,TIF32,eIF3-p170,eIF3-theta,p180,p185,Epigenetics & Nuclear Signaling,RNA Binding,Translation Control,EIF3A
    分子量
    162 kDa/166 kDa
    基因ID
    8661
    UniProt
    Q14152
    途径
    Ribonucleoprotein Complex Subunit Organization
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