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IGF2R 抗体

IGF2R 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7101574
发货至: 中国
  • 抗原 See all IGF2R 抗体
    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
    适用
    • 88
    • 36
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    宿主
    • 67
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    克隆类型
    • 67
    • 23
    单克隆
    标记
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    This IGF2R antibody is un-conjugated
    应用范围
    • 33
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    • 28
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    Western Blotting (WB), Immunofluorescence (IF)
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human Cation-independent Cation-independent M6PR (IGF2R) (IGF2R)
    亚型
    IgG
    Top Product
    Discover our top product IGF2R Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
    别名
    IGF2R (IGF2R 产品)
    别名
    CD222 antibody, CIMPR antibody, M6P-R antibody, MPR1 antibody, MPRI antibody, AI661837 antibody, CI-MPR antibody, M6P/IGF2R antibody, Mpr300 antibody, mpri antibody, cd222 antibody, cimpr antibody, m6p-r antibody, insulin like growth factor 2 receptor antibody, insulin-like growth factor 2 receptor antibody, IGF2R antibody, Igf2r antibody, igf2r antibody
    背景
    This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele, however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015],CD222, CI-M6PR, CIMPR, M6P-R, M6P/IGF2R, MPR 300, MPR1, MPR300, MPRI,CDs,Cell Intrinsic Innate Immunity Signaling Pathway,Immunology & Inflammation,Signal Transduction,IGF2R
    分子量
    274 kDa
    基因ID
    3482
    UniProt
    P11717
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