Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.,ARHGEF1,GEF1,LBCL2,LSC,P115-RHOGEF,SUB1.5,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Microtubules,ARHGEF1