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PLAT 抗体

PLAT 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7101650
发货至: 中国
  • 抗原 See all PLAT 抗体
    PLAT (Plasminogen Activator, Tissue (PLAT))
    适用
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    宿主
    • 95
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    克隆类型
    • 110
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    单克隆
    标记
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    This PLAT antibody is un-conjugated
    应用范围
    • 96
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    Western Blotting (WB), Immunofluorescence (IF)
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human tPA/tPA/PLAT
    亚型
    IgG
    Top Product
    Discover our top product PLAT Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PLAT (Plasminogen Activator, Tissue (PLAT))
    别名
    PLAT (PLAT 产品)
    别名
    T-PA antibody, TPA antibody, AU020998 antibody, AW212668 antibody, D8Ertd2e antibody, tPA antibody, PATISS antibody, tpa antibody, Plat antibody, plat antibody, t-pa antibody, plasminogen activator, tissue type antibody, plasminogen activator, tissue antibody, chromosome 20 open reading frame 181 antibody, plasminogen activator, tissue L homeolog antibody, PLAT antibody, Plat antibody, plat antibody, C20orf181 antibody, plat.L antibody
    背景
    This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016],T-PA, TPA,Blood,Blood_Serum Proteins,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Endocrine & Metabolism,Hypoxia,Ubiquitin,PLAT
    分子量
    63 kDa
    基因ID
    5327
    UniProt
    P00750
    途径
    Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome
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