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APC 抗体 (AA 2544-2843)

Name: APC 抗体 (AA 2544-2843)
Brand: antibodies-online
SKU: ABIN1678690
Availability: OutOfStock

APC 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

Immunohistochemistry of paraffin-embedded human breast cancer using APC antibody (ABIN1678689, ABIN1678690, ABIN5664154 and ABIN6219837) at dilution of 1:200 (40x lens). (APC 抗体 (AA 2544-2843))

IHC

Western blot analysis of extracts of various cell lines, using APC antibody (ABIN1678689, ABIN1678690, ABIN5664154 and ABIN6219837) at 1:1000 dilution. (APC 抗体 (AA 2544-2843))

Immunohistochemistry of paraffin-embedded human lung using APC antibody (ABIN1678689, ABIN1678690, ABIN5664154 and ABIN6219837) at dilution of 1:200 (40x lens). (APC 抗体 (AA 2544-2843))

IHC

Immunohistochemistry of paraffin-embedded human colon using APC antibody (ABIN1678689, ABIN1678690, ABIN5664154 and ABIN6219837) at dilution of 1:200 (40x lens). (APC 抗体 (AA 2544-2843))

IHC

Immunofluorescence analysis of PC-12 cells using APC antibody (ABIN1678689, ABIN1678690, ABIN5664154 and ABIN6219837) at dilution of 1:100. (APC 抗体 (AA 2544-2843))

5 images

产品编号 ABIN1678690

发货至: 中国

Datasheet as PDF

抗原 See all APC 抗体

APC (Adenomatous Polyposis Coli (APC))
抗原表位
21

15

11

8

4

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 2544-2843
适用
63

42

34

6

5

4

3

2

1

1

1

1
人
宿主
94

8

4

2
兔
Compatible Secondaries
克隆类型
86

22
多克隆
标记
58

6

4

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1
This APC antibody is un-conjugated
应用范围
50

30

30

27

26

18

18

11

7

7

3

3

3

2

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

SGTWKREHSK HSSSLPRVST WRRTGSSSSI LSASSESSEK AKSEDEKHVN SISGTKQSKE NQVSAKGTWR KIKENEFSPT NSTSQTVSSG ATNGAESKTL IYQMAPAVSK TEDVWVRIED CPINNPRSGR SPTGNTPPVI DSVSEKANPN IKDSKDNQAK QNVGNGSVPM RTVGLENRLN SFIQVDAPDQ KGTEIKPGQN NPVPVSETNE SSIVERTPFS SSSSSKHSSP SGTVAARVTP FNYNPSPRKS SADSTSARPS QIPTPVNNNT KKRDSKTDST ESSGTQSPKR HSGSYLVTSV

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 2544-2843 of human APC (NP_000029.2).

亚型

IgG

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APC 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Adenomatous Polyposis Coli (APC) (AA 2744-2843) antibody
APC 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3E2 unconjugated

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anti-Adenomatous Polyposis Coli (APC) (AA 2751-2843) antibody
APC 适用: 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

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APC 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Adenomatous Polyposis Coli (APC) antibody
APC 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 5F2 unconjugated Recombinant Antibody

anti-Adenomatous Polyposis Coli (APC) antibody
APC 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Adenomatous Polyposis Coli (APC) (C-Term) antibody
APC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Adenomatous Polyposis Coli (APC) (AA 1-2843) antibody
APC 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:200

限制

仅限研究用
缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
抗原

APC (Adenomatous Polyposis Coli (APC))

别名

APC (APC 产品)

别名

dp2 antibody, dp3 antibody, fap antibody, fpc antibody, xapc antibody, dp2.5 antibody, AI047805 antibody, AU020952 antibody, AW124434 antibody, CC1 antibody, Min antibody, mAPC antibody, BTPS2 antibody, DP2 antibody, DP2.5 antibody, DP3 antibody, GS antibody, PPP1R46 antibody, RATAPC antibody, APC1 antibody, APC, WNT signaling pathway regulator antibody, adenomatous polyposis coli antibody, adenomatous polyposis coli protein, putative antibody, adenomatosis polyposis coli antibody, adenomatous polyposis coli L homeolog antibody, APC antibody, apc antibody, Smp_139190 antibody, Apc antibody, apc.L antibody

背景

This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.,APC,BTPS2,DP2,DP2.5,DP3,GS,PPP1R46,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Centrosome,Cell Adhesion,Microtubules,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Neuroscience,Cell Type Marker,Stem Cells,Cardiovascular,Heart,Cardiogenesis,Oligodendrocyte marker,APC

分子量

300 kDa/311 kDa

基因ID

324

UniProt

P25054

途径

WNT signaling, Stem Cell Maintenance, Cell-Cell Junction Organization