PARL 抗体 (C-Term)
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- 抗原 See all PARL 抗体
- PARL (Presenilin Associated, Rhomboid-Like (PARL))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 小鸡, 灵长类
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PARL antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Fluorescence Microscopy (FM)
- Supplier Product No.
- 600-401-j27
- Supplier
- Rockland
- 原理
- PARL Antibody
- 交叉反应 (详细)
- This antibody is specific towards PARL.
- 产品特性
- Synonyms: rabbit anti-PARL antibody, p-beta, Pbeta, presenilin associated rhomboid-like protein mitochondrial, PRO2207, Mitochondrial intramembrane cleaving protease PARL, PSARL
- 纯化方法
- Anti-PARL was affinity purified from monospecific antiserum by immunoaffinity chromatography.
- 过滤
- Sterile filtered
- 免疫原
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Immunogen: PARL affinity purified antibody was prepared from whole rabbit serum produced by repeated immunization from a synthetic peptide corresponding to the C terminus region of human PARL.
Immunogen Type: Conjugated Peptide
- Top Product
- Discover our top product PARL Primary Antibody
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- 应用备注
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Immunohistochemistry Dilution: 1:100-1:500
Application Note: Anti-PARL antibody is useful for ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~42.2 kDa corresponding to the appropriate cell lysate or extract.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 1:20,000 - 1:60,000
IF Microscopy Dilution: 1:100-1:500
Other: User Optimized
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.86 mg/mL
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: None - 储存液
- Without preservative
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 6 months
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- 抗原
- PARL (Presenilin Associated, Rhomboid-Like (PARL))
- 别名
- PARL (PARL 产品)
- 背景
- Background: PARL (presenilin associated, rhomboid-like) encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. Anti-PARL antibodies are ideal for researchers interested in Apoptosis, Alzheimer's Research, Neuroscience, and Mitochondrial Fusion Proteins research.
- 基因ID
- 55486
- NCBI登录号
- NP_061092
- UniProt
- Q9H300
- 途径
- Autophagy
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