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HDAC7 抗体 (N-Term)

HDAC7 适用: 人, 小鼠, 大鼠, 灵长类 WB, ELISA, IHC, FM 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1607889
发货至: 中国
  • 抗原 See all HDAC7 抗体
    HDAC7 (Histone Deacetylase 7 (HDAC7))
    抗原表位
    • 18
    • 15
    • 13
    • 8
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    • 5
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    N-Term
    适用
    • 110
    • 72
    • 53
    • 5
    • 5
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    • 1
    • 1
    人, 小鼠, 大鼠, 灵长类
    宿主
    • 119
    • 6
    克隆类型
    • 113
    • 12
    多克隆
    标记
    • 52
    • 10
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    • 7
    • 4
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    This HDAC7 antibody is un-conjugated
    应用范围
    • 78
    • 49
    • 26
    • 16
    • 14
    • 14
    • 9
    • 4
    • 4
    • 3
    • 2
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Fluorescence Microscopy (FM)
    交叉反应 (详细)
    Cross reactivity with HDAC7 from other sources has not been determined.
    纯度
    Anti-HDAC7 was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific towards HDAC7. A BLAST analysis was used to suggest cross-reactivity with Human, Mouse, Rat and Primate based on 100 % sequence homology.
    内毒素水平
    Low Endotoxin : No
    免疫原
    HDAC7 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the N terminal region of human HDAC7.
    Immunogen Type: Peptide
    Top Product
    Discover our top product HDAC7 Primary Antibody
  • 应用备注
    Anti-HDAC7 antibody is useful for ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~103kDa and isoforms at ~70, and 40 kDa corresponding to the appropriate cell lysate or extract.
    ELISA Dilution: 1:20.000 - 1:60.000
    Immunohistochemistry Dilution: 1:100-1:500
    IF Microscopy Dilution: 1:100-1:500
    Western Blot Dilution: 1 µg/mL
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.55 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Stabilizer: 50 % (v/v) Glycerol
    储存条件
    4 °C/-20 °C
    储存方法
    Store vial at -20 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    Expiration date is six (6) months from date of opening.
  • 抗原
    HDAC7 (Histone Deacetylase 7 (HDAC7))
    别名
    HDAC7 (HDAC7 产品)
    别名
    HD7A antibody, HDAC7A antibody, 5830434K02Rik antibody, HD7 antibody, HD7a antibody, Hdac7a antibody, mFLJ00062 antibody, hdac7a antibody, K2K18.5 antibody, K2K18_5 antibody, histone deacetylase7 antibody, histone deacetylase 7 antibody, histone deacetylase7 antibody, HDAC7 antibody, Hdac7 antibody, hdac7 antibody, HDA7 antibody
    背景
    HDAC7 is a member of the class II mammalian histone deacetylases, which plays an important role in modulating the eukaryotic chromatin structure. Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. It is an active component of different transcriptional corepressor complexes that can be recruited to specific promoter regions via interactions with a growing number of sequence specific transcriptional factors. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription. Anti-HDAC7 antibodies are ideal for researches interested in Breast Cancer, Cancer, Cell Cycle and Replication, Chromatin Research, Epigenetics, and Histone Deacetylases research. Synonyms: DKFZP586J0917, EC 3.5.1.98, HD7, HD7A, HD7a, HDAC7AFLJ99588, histone deacetylase 7, Histone deacetylase 7ADKFZp586J0917
    基因ID
    51564
    NCBI登录号
    NP_001091886
    UniProt
    Q8WUI4
    途径
    Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development
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