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APP 抗体 (N-Term)

Name: APP 抗体 (N-Term)
SKU: ABIN1607881
Availability: OutOfStock

Rockland 600-401-j14 APP 适用: 人 WB, ELISA, IHC, IF, FM, DB, MA 宿主: 兔 Polyclonal unconjugated

Western Blot of Rabbit Anti-beta Amyloid pyro E3 antibody. (APP 抗体 (N-Term))

Immunofluorescence Microscopy of Rabbit Anti-beta Amyloid pyro E3 antibody. (APP 抗体 (N-Term))

3 images

产品编号 ABIN1607881

Supplier Product No.: 600-401-j14

发货至: 中国

Datasheet as PDF

抗原 See all APP 抗体

APP (Amyloid beta (A4) Precursor Protein (APP))
抗原表位
30

27

24

22

17

16

11

8

8

8

7

6

6

5

4

4

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
234

113

107

12

10

9

9

9

9

8

7

5

4

4

3

1

1

1

1

1
人
宿主
197

73

4

4

2
兔
Compatible Secondaries
克隆类型
217

63
多克隆
标记
146

24

19

18

7

6

4

4

4

4

4

4

4

4

4

4

4

2

2

2

2

2

2

2

2

1
This APP antibody is un-conjugated
应用范围
181

132

77

52

52

44

39

29

27

15

15

6

4

3

2

2

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Fluorescence Microscopy (FM), Dot Blot (DB), Multiplex Assay (MA)

Supplier Product No.

600-401-j14

Supplier

Rockland

原理

Beta Amyloid pyro E3 Antibody

交叉反应（详细）

This antibody contains no reactivity towards the 1-42 ABeta peptide.

产品特性

Synonyms: rabbit anti-Beta Amyloid pyro E3 Antibody, ß-amyloid pyro E3, Alzheimer disease amyloid protein, Beta amyloid, A-beta, ABPP, APPI

纯化方法

Anti-Beta Amyloid pyro Glu3 was affinity purified from monospecific antiserum by immunoaffinity chromatography.

过滤

Sterile filtered

免疫原

Immunogen: Beta Amyloid [Pyro Glu3] affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the N-terminus 3-pyro E start point of human beta Amyloid.
Immunogen Type: Conjugated Peptide

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anti-Amyloid beta (A4) Precursor Protein (APP) antibody
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应用备注

Immunohistochemistry Dilution: 1:100-1:500
Application Note: Anti-Beta Amyloid pyro Glu3 has been tested in dot blot, ELISA, Western Blot, and Immunostaining. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~86.9 kDa corresponding to the appropriate cell lysate or extract.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 1:20,000 - 1:60,000
IF Microscopy Dilution: 1:100-1:500
Other: User Optimized

限制

仅限研究用
状态

Liquid

浓度

0.5 mg/mL

缓冲液

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

有效期

6 months
抗原

APP (Amyloid beta (A4) Precursor Protein (APP))

别名

APP (APP 产品)

背景

Background: The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. Beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. Beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. Beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. Beta Amyloid antibodies and peptides have been developed as tools for elucidating the biology of Alzheimer's disease. Anti-beta Amyloid [Pyro Glu11] Antibody is ideal for researchers interested in Alzheimer's Research, Cell Cycle and Replication, and Neuroscience research.

基因ID

351

NCBI登录号

NP_000475

UniProt

P05067

途径

Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour