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- 抗原 See all MYH6 抗体
- MYH6 (Myosin Heavy Chain 6, Cardiac Muscle, alpha (MYH6))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MYH6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应 （详细）
- Cross reactivity with myosin6 from other sources have not been determined.
- 纯度
- Anti-Myosin-6 is directed against the human myosin-6 protein. The product was prepared from monospecific antiserum by delipidation and defibrination. A BLAST analysis was used to suggest reactivity with human only.
- 内毒素水平
- Low Endotoxin : No
- 免疫原
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Anti-Myosin-6 was prepared from whole rabbit serum produced by repeated immunizations with a truncated myosin-6 construct expressed in SF9 insect cells corresponding to human myosyn-6 protein.
Immunogen Type: Recombinant Protein - Top Product
- Discover our top product MYH6 Primary Antibody
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anti-Myosin Heavy Chain 6, Cardiac Muscle, alpha (MYH6) (AA 419-666) antibody
MYH6 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myosin Heavy Chain 6, Cardiac Muscle, alpha (MYH6) antibodyMYH6 适用: 大鼠, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Myosin Heavy Chain 6, Cardiac Muscle, alpha (MYH6) (AA 894-1132) antibodyMYH6 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myosin Heavy Chain 6, Cardiac Muscle, alpha (MYH6) (AA 1-250) antibodyMYH6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Myosin Heavy Chain 6, Cardiac Muscle, alpha (MYH6) (AA 341-390) antibodyMYH6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myosin Heavy Chain 6, Cardiac Muscle, alpha (MYH6) (AA 833-867) antibodyMYH6 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB49145 unconjugated
anti-Myosin Heavy Chain 6, Cardiac Muscle, alpha (MYH6) (AA 856-1116) antibodyMYH6 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myosin Heavy Chain 6, Cardiac Muscle, alpha (MYH6) (AA 1747-1938) antibodyMYH6 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Myosin-6 antibody has been tested for use in ELISA and western blot. For western blots expect a band of approximately 150 kDa in size corresponding to truncated myosin-6 protein. Specific conditions for reactivity should be optimized by the end user.
ELISA Dilution: 1:10.000
Western Blot Dilution: 1:1000 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 25 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 注意事项
- Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store vial at -20 °C or below prior to opening. This vial contains a relatively low volume of reagent (25 µL). To minimize loss of volume dilute 1:10 by adding 225 µL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below.
- 有效期
- Expiration date is one (1) year from date of opening.
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- 抗原
- MYH6 (Myosin Heavy Chain 6, Cardiac Muscle, alpha (MYH6))
- 别名
- Myosin 6 (MYH6 产品)
- 别名
- Myhca antibody, ASD3 antibody, CMD1EE antibody, CMH14 antibody, MYHC antibody, MYHCA antibody, SSS3 antibody, alpha-MHC antibody, A830009F23Rik antibody, AA517445 antibody, Myhc-a antibody, amhc antibody, MYH6 antibody, P-MHC antibody, VMHC1 antibody, myosin antibody, myosin heavy chain 6 antibody, myosin, heavy polypeptide 6, cardiac muscle, alpha antibody, myosin, heavy chain 6, cardiac muscle, alpha antibody, myosin-6 antibody, myosin, heavy chain 15 antibody, Myh6 antibody, MYH6 antibody, LOC101120580 antibody, myh6 antibody, MYH15 antibody
- 背景
- Myosin VI is a myosin superfamily member with unique and intriguing features that allow it to fill a still-expanding number of cell biological roles. This actin-based motor produces force that acts towards the minus end of actin filaments, which is the opposite direction to all other characterized myosins. In mammalian cells, myosin VI is localized to endocytic vesicles, membrane ruffles, the cytosol and the Golgi complex. Its motor function is essential for several physiological functions of the cell, including normal rates of endocytosis, maintenance of Golgi morphology and protein secretion. Myosin VI regulates epithelial cell migration and plays a role in the maintenance of adhesive cellular contacts within epithelial cell layers. It is highly expressed in ovarian cancers and prostate cancers and its expression level, which is upregulated by DNA damage in a p53-dependent manner, correlates with the potential of the tumor to disseminate. More recently, myosin VI has been found involved in EGFR endocytosis through a clathrin dependent mechanism. Synonyms: MyosinVI, Unconventional myosin 6
- 基因ID
- 3799
- NCBI登录号
- NP_004512
- UniProt
- P33176
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