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CCBE1 抗体 (AA 159-251)

CCBE1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1589917
发货至: 中国
  • 抗原 See all CCBE1 抗体
    CCBE1 (Collagen and Calcium Binding EGF Domains 1 (CCBE1))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 159-251
    适用
    • 32
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 31
    • 2
    克隆类型
    • 33
    多克隆
    标记
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCBE1 antibody is un-conjugated
    应用范围
    • 26
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    原理
    ccbe1 antibody
    特异性
    Recombinant human ccbe1 (Tyr35-Pro406) derived from Sf9 insect cells
    产品特性
    Chromosomal location: 18q21.32
    纯化方法
    Protein A purified
    免疫原
    Highly pure (>98%) recombinant human ccbe1 (Cys159-Leu251) derived from E. coli.
    亚型
    IgG
    Top Product
    Discover our top product CCBE1 Primary Antibody
  • 应用备注
    Western Blot: Use 2-5 μg/mL
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
    缓冲液
    PBS
    注意事项
    Centrifuge vial prior to opening. Avoid repeated freeze-thaw cycles.
    储存条件
    4 °C,-20 °C
    储存方法
    The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
    有效期
    24 months
  • 抗原
    CCBE1 (Collagen and Calcium Binding EGF Domains 1 (CCBE1))
    别名
    ccbe1 (CCBE1 产品)
    别名
    4933426F18Rik antibody, 9430093N24Rik antibody, mKIAA1983 antibody, RGD1307670 antibody, fof antibody, collagen and calcium binding EGF domains 1 antibody, CCBE1 antibody, Ccbe1 antibody, ccbe1 antibody
    背景
    Collagen and calcium binding EGF domains 1, KIAA1983,The lymphatic system comprises a vascular system separate from the cardiovascular system, essential for immune responses, fluid homeostasis and fat absorption. Lymphatic vessels develop in a complex process termed lymphangiogenesis that involves budding, migration and proliferation of lymphatic endothelial progenitor cells. A few genes, such as FLT4, FOXC2 and SOX18, are known to be critically involved in lymph vessel formation in humans. Lymphedema, lymphangiectasias, mental retardation and unusual facial characteristics define the autosomal recessive Hennekam syndrome. Homozygosity mapping identified a critical chromosomal region containing ccbe1, encoding Collagen and Calcium-Binding EGF-domain-1, a secreted protein which is required for embryonic lymphangiogenesis in zebrafish. ccbe1 is not expressed in endothelial cells of lymph vessels, and it may be a component of the extracellular matrix. In zebrafish, ccbe1 expression was observed along the earliest migration routes of endothelial cells that sprout from the posterior cardinal vein and migrate circuitously before developing into lymphatic vessels. ccbe1 might therefore be involved in guidance of these migrating cells.
    基因ID
    147372
    NCBI登录号
    NM_133459, NP_597716
    UniProt
    Q6UXH8
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