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VEGFC 抗体

VEGFC 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1589911
发货至: 中国
  • 抗原 See all VEGFC 抗体
    VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
    适用
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    大鼠
    宿主
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    克隆类型
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    多克隆
    标记
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    This VEGFC antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    原理
    VEGF-C antibody
    特异性
    Recombinant rat VEGF-C
    产品特性
    Chromosomal location: 16p11
    Produced from sera of rabbits immunized with highly pure recombinant rat dNdC-VEGF-C.
    纯化方法
    Anti-rat VEGF-C IgG was purified by affinity chromatography with immobilized Protein A.
    免疫原
    Recombinant rat VEGF-C (ABIN1589785)
    亚型
    IgG
    Top Product
    Discover our top product VEGFC Primary Antibody
  • 应用备注
    Western Blot: Use 2-5 μg/mL
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
    缓冲液
    PBS
    注意事项
    Centrifuge vial prior to opening.
    储存条件
    4 °C,-20 °C
    储存方法
    The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
    有效期
    24 months
  • Maertens, Erpicum, Detry, Blacher, Lenoir, Carnet, Péqueux, Cataldo, Lecomte, Paupert, Noel: "Bone marrow-derived mesenchymal stem cells drive lymphangiogenesis." in: PLoS ONE, Vol. 9, Issue 9, pp. e106976, (2014) (PubMed).

  • 抗原
    VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
    别名
    VEGF-C (VEGFC 产品)
    别名
    VEGFC antibody, vegf-c antibody, xvegf-c antibody, Flt4-L antibody, VRP antibody, AW228853 antibody, VEGF-C antibody, vascular endothelial growth factor c antibody, vascular endothelial growth factor C antibody, vascular endothelial growth factor C S homeolog antibody, vegfc antibody, VEGFC antibody, vegfc.S antibody, Vegfc antibody
    背景
    Vascular endothelial growth factor C, Vegfc,VEGF-C, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-C is expressed in various tissues, but is not produced in peripheral blood lymphocytes. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-C may play a role in the formation of the venous and lymphatic vascular systems. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant, fully processed rat VEGF-C is a 16-18 kDa non-disulfide linked homodimeric protein consisting of two 116 amino acid polypeptide chains. Due to glycosylation the protein migrates as a 20.0-22.0 kDa band under non-reducing condition.
    基因ID
    114111
    NCBI登录号
    NM_053653, NP_446105
    UniProt
    O35757
    途径
    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2
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