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- 抗原 See all VEGFC 抗体
- VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This VEGFC antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- VEGF-C antibody
- 特异性
- Recombinant rat VEGF-C
- 产品特性
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Chromosomal location: 16p11
Produced from sera of rabbits immunized with highly pure recombinant rat dNdC-VEGF-C. - 纯化方法
- Anti-rat VEGF-C IgG was purified by affinity chromatography with immobilized Protein A.
- 免疫原
- Recombinant rat VEGF-C (ABIN1589785)
- 亚型
- IgG
- Top Product
- Discover our top product VEGFC Primary Antibody
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- 应用备注
- Western Blot: Use 2-5 μg/mL
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
- 缓冲液
- PBS
- 注意事项
- Centrifuge vial prior to opening.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
- 有效期
- 24 months
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Bone marrow-derived mesenchymal stem cells drive lymphangiogenesis." in: PLoS ONE, Vol. 9, Issue 9, pp. e106976, (2014) (PubMed).
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Bone marrow-derived mesenchymal stem cells drive lymphangiogenesis." in: PLoS ONE, Vol. 9, Issue 9, pp. e106976, (2014) (PubMed).
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- 抗原
- VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
- 别名
- VEGF-C (VEGFC 产品)
- 别名
- VEGFC antibody, vegf-c antibody, xvegf-c antibody, Flt4-L antibody, VRP antibody, AW228853 antibody, VEGF-C antibody, vascular endothelial growth factor c antibody, vascular endothelial growth factor C antibody, vascular endothelial growth factor C S homeolog antibody, vegfc antibody, VEGFC antibody, vegfc.S antibody, Vegfc antibody
- 背景
- Vascular endothelial growth factor C, Vegfc,VEGF-C, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-C is expressed in various tissues, but is not produced in peripheral blood lymphocytes. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-C may play a role in the formation of the venous and lymphatic vascular systems. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant, fully processed rat VEGF-C is a 16-18 kDa non-disulfide linked homodimeric protein consisting of two 116 amino acid polypeptide chains. Due to glycosylation the protein migrates as a 20.0-22.0 kDa band under non-reducing condition.
- 基因ID
- 114111
- NCBI登录号
- NM_053653, NP_446105
- UniProt
- O35757
- 途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2
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