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- 抗原 See all PROX1 抗体
- PROX1 (Prospero Homeobox 1 (PROX1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PROX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 原理
- Prox-1 antibody
- 特异性
- Recombinant human Prox-1
- 产品特性
- Chromosomal location: 1q32.2-q32.3
- 纯化方法
- Protein A purified
- 免疫原
- Recombinant human Prox-1 (ABIN1589681)
- 亚型
- IgG
- Top Product
- Discover our top product PROX1 Primary Antibody
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- 应用备注
- Western Blot: Use 1-5 μg/mL
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
- 缓冲液
- 0.5X PBS, pH 7.2
- 注意事项
- Centrifuge vial prior to opening. Avoid repeated freeze-thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
- 有效期
- 24 months
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Coordinated lymphangiogenesis is critical in lymph node development and maturation." in: Developmental dynamics : an official publication of the American Association of Anatomists, (2016) (PubMed).
: "Inhibition of VEGFR-3 activation in tumor-draining lymph nodes suppresses the outgrowth of lymph node metastases in the MT-450 syngeneic rat breast cancer model." in: Clinical & experimental metastasis, Vol. 31, Issue 3, pp. 351-65, (2014) (PubMed).
: "Prox1 regulates Olig2 expression to modulate binary fate decisions in spinal cord neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 47, pp. 15816-31, (2014) (PubMed).
: "Angiogenesis in canine mammary tumours: a morphometric and prognostic study." in: Journal of comparative pathology, Vol. 150, Issue 2-3, pp. 175-83, (2014) (PubMed).
: "An immunohistochemical study of angiokeratomas of children." in: The American Journal of dermatopathology, Vol. 36, Issue 10, pp. 796-9, (2014) (PubMed).
: "Expression of PROX-1 in oral Kaposi's sarcoma spindle cells." in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, Vol. 43, Issue 2, pp. 132-6, (2014) (PubMed).
: "Fusing VE-cadherin to ?-catenin impairs fetal liver hematopoiesis and lymph but not blood vessel formation." in: Molecular and cellular biology, Vol. 34, Issue 9, pp. 1634-48, (2014) (PubMed).
: "Involvement of neurons and retinoic acid in lymphatic development: new insights in increased nuchal translucency." in: Prenatal diagnosis, Vol. 34, Issue 13, pp. 1312-9, (2014) (PubMed).
: "De novo hem- and lymphangiogenesis by endothelial progenitor and mesenchymal stem cells in immunocompetent mice." in: Cellular and molecular life sciences : CMLS, Vol. 71, Issue 8, pp. 1513-27, (2014) (PubMed).
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Coordinated lymphangiogenesis is critical in lymph node development and maturation." in: Developmental dynamics : an official publication of the American Association of Anatomists, (2016) (PubMed).
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- 抗原
- PROX1 (Prospero Homeobox 1 (PROX1))
- 别名
- Prox-1 (PROX1 产品)
- 别名
- xprox1 antibody, prospero antibody, PROX1 antibody, LOC100232600 antibody, A230003G05Rik antibody, prox1 antibody, zgc:111888 antibody, prospero homeobox 1 antibody, prospero homeobox 1 L homeolog antibody, prospero homeobox 1a antibody, PROX1 antibody, prox1.L antibody, prox1 antibody, Prox1 antibody, prox1a antibody
- 背景
- PROX1, W117m,Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lymphatic vessels from blood vessels. Prox-1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells. Produced from sera of rabbits immunized with the recombinant highly conserved C-terminal part of the homeobox transcription factor Prox-1.
- 基因ID
- 5629
- NCBI登录号
- NM_002763, NP_002754
- UniProt
- Q92786
- 途径
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
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