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GLG1 抗体

GLG1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1589833
发货至: 中国
  • 抗原 See all GLG1 抗体
    GLG1 (Golgi Glycoprotein 1 (GLG1))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This GLG1 antibody is un-conjugated
    应用范围
    • 32
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    Western Blotting (WB)
    原理
    ESL-1 antibody
    特异性
    Recombinant human soluble ESL-1
    纯化方法
    Protein A purified
    免疫原
    Recombinant human soluble ESL-1
    亚型
    IgG
    Top Product
    Discover our top product GLG1 Primary Antibody
  • 应用备注
    Western Blot: Use 1-5 μg/mL
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
    缓冲液
    PBS
    注意事项
    Centrifuge vial prior to opening.
    储存条件
    4 °C,-20 °C
    储存方法
    The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
    有效期
    24 months
  • 抗原
    GLG1 (Golgi Glycoprotein 1 (GLG1))
    别名
    ESL-1 (GLG1 产品)
    别名
    AI593353 antibody, AW537898 antibody, CFR antibody, CFR-1 antibody, ESL-1 antibody, MG-160 antibody, MG160 antibody, Selel antibody, ESL1 antibody, LTCP-1 antibody, golgi glycoprotein 1 antibody, Golgi apparatus protein 1 antibody, golgi apparatus protein 1 antibody, GLG1 antibody, LOC100175586 antibody, Glg1 antibody
    背景
    Golgi apparatus protein-1, E-selectin ligand-1, Cysteine-rich fibroblast growth factor receptor,E-Selectin ligand-1/ESL-1 (GLG1, Golgi complex-Localized Glycoprotein 1, CFR1, MG160 and Cysteine-rich FGF receptor) is a 150-160 kDa glycoprotein. The amino acid sequence of MG160, a membrane sialoglycoprotein of the medial cisternae of the rat Golgi apparatus, is more than 90 % identical with CFR, a fibroblast growth factor (FGF) binding protein of chicken membranes, and with ESL-1, a ligand for E-selectin of plasma membranes of myeloid cells, furthermore, MG160, isolated by immunoaffinity chromatography from rat brain membranes, binds to basic FGF. The protein has a large luminal domain composed of an initial Proline-Glutamine-rich segment, encoded by an uninterrupted exonic sequence of several CAG-CAA repeats. Expansion of CAG repeats has been implicated in the etiology of several neurodegenerative diseases. The Proline-Glutamine-rich segment is followed by 16 cysteine-rich repeats that contain five potential Asparagine-linked glycosylation sites, which are conserved in the human, rat, mouse, and chicken. The large extracellular domain of the protein is followed by a single transmembrane domain and a 13-amino-acid cytoplasmic carboxy-terminal tail, which is identical to that in the chicken, rat, and mouse. It is expressed in both Golgi and/or the cell membrane of multiple cell typs, including liver stellate cells, neurons, cardiac myocytes, monocytes and bronchial epithelial cells. In the blood, GLG1/ESL-1 collaborates with PSGL-1 to mediate leukocyte binding to endothelial cell surfaces
    基因ID
    2734
    NCBI登录号
    NM_001145666, NP_001139138
    UniProt
    Q92896
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