VEGF-Apan (Peptide) (N-Term) 抗体
适用: 人
IP, WB
宿主: 兔
Polyclonal
unconjugated
-
- 抗原
- VEGF-Apan (Peptide)
- 抗原表位
- N-Term
- 适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- 非结合性
- 应用范围
- Immunoprecipitation (IP), Western Blotting (WB)
- 原理
- VEGF-Apan (Peptide) antibody
- 特异性
- N-terminal peptide (20aa) of native human VEGF165
- 产品特性
-
Chromosomal location: 6p12
Produced from sera of rabbits immunized with a highly purified N-terminal peptide of human VEGF-A. - 纯化方法
- Anti-VEGF-A was purified by affinity chromatography with immobilized Protein A.
- 免疫原
- N-terminal peptide (20aa) of native human VEGF165
- 亚型
- IgG
-
-
- 应用备注
- IP: Use 1-5 μg/mL
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
- 缓冲液
- PBS
- 注意事项
- Centrifuge vial prior to opening.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
- 有效期
- 24 months
-
- 抗原
- VEGF-Apan (Peptide)
- 背景
- VEGFA, VPF, VEGF, MVCD1,Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF) or vasculotropin, is a homodimeric 34 - 42 kDa, heparin-binding glycoprotein with potent angiogenic, mitogenic and vascular permeability-enhancing activities specific for endothelial cells. Different isoforms can be generated by differential splicing (e.g. VEGF165). All eight cysteine residues involved in intra- and inter-chain disulfide bonds are conserved among these growth factors. A cDNA encoding a protein having a 53 % amino acid sequence homology in the PDGF-like region of VEGF has been isolated from a human placental cDNA library. This protein, named placenta growth factor (PlGF), is now recognized to be a member of the VEGF family of growth factors. Two receptor tyrosine kinases have been described as putative VEGF receptors. Flt-1 (fms-like tyrosine kinase), and KDR (kinase-insert-domain-containing receptor) proteins have been shown to bind VEGF-A with high affinity. In vitro, VEGF is a potent endothelial cell mitogen. The antibody is against the N-terminus and will recognize all VEGF-A isoforms.
- 基因ID
- 7422
- NCBI登录号
- NM_001171626, NP_001165097
- UniProt
- P15692
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