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HTR2A 抗体 (3rd Cytoplasmic Loop)

HTR2A 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1574026
发货至: 中国
  • 抗原 See all HTR2A 抗体
    HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
    抗原表位
    • 16
    • 15
    • 7
    • 5
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    • 4
    • 3
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    • 1
    • 1
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    3rd Cytoplasmic Loop
    适用
    • 66
    • 54
    • 51
    • 7
    • 5
    • 3
    • 1
    • 1
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    宿主
    • 71
    • 1
    克隆类型
    • 72
    多克隆
    标记
    • 21
    • 5
    • 5
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    • 2
    • 2
    • 2
    • 2
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    This HTR2A antibody is un-conjugated
    应用范围
    • 52
    • 27
    • 26
    • 21
    • 12
    • 10
    • 7
    • 6
    • 5
    • 1
    • 1
    Western Blotting (WB), ELISA
    特异性
    Rabbit Anti-5HT2A Receptor Polyclonal Antibody detects endogenous levels of 5HT2A receptor.
    纯化方法
    Immunoaffinity chromatography
    免疫原
    Synthetic peptide (KLH-coupled) derived from the third intracellular domain loop of human 5HT2A receptor .
    亚型
    IgG
    Top Product
    Discover our top product HTR2A Primary Antibody
  • 应用备注
    Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

    ELISA: 0.05-0.2 µg/mL
    Western blot: 0.5-2 µg/mL
    Other applications: user-optimized
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4, containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    储存条件
    4 °C/-20 °C
    储存方法
    The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
  • 抗原
    HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
    别名
    5HT2A Receptor (HTR2A 产品)
    别名
    5-HT2A antibody, HTR2 antibody, 5-HT-2 antibody, 5-HT-2A antibody, 5-HTR2A antibody, LOC100009461 antibody, E030013E04 antibody, Htr-2 antibody, Htr2 antibody, 5Ht-2 antibody, 5HT2A antibody, 5HTR2A antibody, HTR2A antibody, Htr2a antibody, 5HT2 antibody, 5-hydroxytryptamine receptor 2A antibody, 5-hydroxytryptamine (serotonin) receptor 2A antibody, HTR2A antibody, Htr2a antibody
    背景
    5HT are receptors for neurotransmitter and peripheral signal mediator serotonin. It is also known as 5-hydroxytryptamine or 5HT. 5HT receptors mediate the effects of serotonin as the endogenous ligand and of a broad range of pharmaceutical and hallucinogenic drugs. Specifically, 5HT receptors affect the release of other neurotransmitters such as glutamate, dopamine, and GABA as well as their activities.5HT2A is a type of receptor belongs to the serotonin receptor family and is one member of G protein coupled receptor (GPCR) family. 5HT2A is involved in the contraction of tracheal smooth muscle, bronchoconstriction, and the control of aldosterone production. The receptor also happens to be necessary for the spread of the human polyoma virus called JC virus. 5HT2A is widely expressed throughout the central nervous system (CNS). It is expressed near most of the serotoninergic terminal rich areas, including neocortex and olfactory tubercle. Increased stimulation of 5HT2A receptors seems to oppose the therapeutic actions of increased stimulation of other serotonin receptors in anti-depressant and anxiolytic treatments.Rabbit Anti-5HT2A Receptor Polyclonal Antibody is developed in rabbit hosts using a KLH-coupled synthetic peptide derived from the third intracellular domain loop of human 5HT2A receptor (Swiss Prot: P28223).
    途径
    JAK/STAT Signaling, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process
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