我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

CCR5 抗体 (AA 1-22)

Name: CCR5 抗体 (AA 1-22)
Brand: antibodies-online
SKU: ABIN1558080
Availability: OutOfStock

CCR5 适用: 人 WB, ELISA, FACS, IP, ICC 宿主: 小鼠 Monoclonal T21-8 unconjugated

Flow cytometry surface staining pattern of human peripheral blood stained using anti-human CD195 (T21/8) purified antibody (concentration in sample 3 μg/mL) GAM APC. (CCR5 抗体 (AA 1-22))

FACS

Separation of human CD195 positive lymphocytes (red-filled) from CD195 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD195 (T21/8) purified antibody (concentration in sample 3 μg/mL) GAM APC. (CCR5 抗体 (AA 1-22))

FACS

2 images

(3 references)

产品编号 ABIN1558080

发货至: 中国

Datasheet as PDF

抗原 See all CCR5 抗体

CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
抗原表位
16

13

11

7

7

6

6

6

6

6

5

5

4

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-22
适用
145

44

37

10

2

1

1

1

1
人
宿主
106

31

13

4

1
小鼠
Compatible Secondaries
克隆类型
109

40

3
单克隆
标记
82

13

11

7

5

4

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CCR5 antibody is un-conjugated
应用范围
92

68

57

21

18

16

16

14

14

13

6

4

2

2

2

2

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

特异性

The mouse monoclonal antibody T21/8 recognizes an extracellular epitope on the N-teminus of CD195, an approximately 45 kDa G-protein coupled receptor 1 family protein expressed on resting T cells, monocytes, macrophages, and immature dendritic cells.

交叉反应（详细）

Human

纯化方法

Purified by protein-A affinity chromatography.

纯度

> 95 % (by SDS-PAGE)

免疫原

CCR5 peptide (Met1-Lys22) KLH conjugate

克隆位点

T21-8

亚型

IgG1 kappa

Top Product

Discover our top product CCR5 Primary Antibody
anti-Chemokine (C-C Motif) Receptor 5 (CCR5) antibody
CCR5 适用: 人 IHC (fro) 宿主: 小鼠 Monoclonal 12D1 unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) antibody
CCR5 适用: 人, 大鼠 WB, ELISA, FACS, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 6G11D1 unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 19-34), (N-Term) antibody
CCR5 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) antibody
CCR5 适用: 人 WB, ELISA, FACS, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 6H3D5 unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 201-300) antibody
CCR5 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (fro), IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 151-200) antibody
CCR5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 1-352) antibody
CCR5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 1-352) antibody
CCR5 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (pSer336) antibody
CCR5 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 100-200) antibody
CCR5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Western blotting: Do not boil cell lysates prior to SDS-PAGE.
Flow cytometry: Recommended dilution: 1-4 μg/mL

限制

仅限研究用
浓度

1 mg/mL

缓冲液

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Do not freeze.

储存条件

4 °C

储存方法

Store at 2-8°C. Do not freeze.
Monde, Maeda, Tanaka, Harada, Yusa: "Gp120 V3-dependent impairment of R5 HIV-1 infectivity due to virion-incorporated CCR5." in: The Journal of biological chemistry, Vol. 282, Issue 51, pp. 36923-32, (2007) (PubMed).

Hüttenrauch, Pollok-Kopp, Oppermann: "G protein-coupled receptor kinases promote phosphorylation and beta-arrestin-mediated internalization of CCR5 homo- and hetero-oligomers." in: The Journal of biological chemistry, Vol. 280, Issue 45, pp. 37503-15, (2005) (PubMed).

Pollok-Kopp, Schwarze, Baradari, Oppermann: "Analysis of ligand-stimulated CC chemokine receptor 5 (CCR5) phosphorylation in intact cells using phosphosite-specific antibodies." in: The Journal of biological chemistry, Vol. 278, Issue 4, pp. 2190-8, (2003) (PubMed).
抗原

CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

别名

CD195 / CCR5 (CCR5 产品)

别名

CC-CKR-5 antibody, CCCKR5 antibody, CCR-5 antibody, CD195 antibody, CKR-5 antibody, CKR5 antibody, CMKBR5 antibody, IDDM22 antibody, Ckr5 antibody, Cmkbr5 antibody, CCR1-L antibody, GPCR antibody, CCR5 antibody, AM4-7 antibody, C-C motif chemokine receptor 5 (gene/pseudogene) antibody, chemokine (C-C motif) receptor 5 antibody, C-C motif chemokine receptor 5 antibody, CCR5 antibody, Ccr5 antibody

背景

C-C motif chemokine receptor 5,CD195 / CCR5 (also known as CKR-5) is a receptor for inflammatory CC-chemokines (characterized by a pair of adjacent cysteine residues), such as MIP-1 alpha, MIP-1 beta, or RANTES. It is a G protein-associated seven-pass transmembrane protein expressed on resting T cells with memory/effector phenotype, monocytes, macrophages and immature dendritic cells. This chemokine receptor regulates the activation and directed migration of leukocytes. Importantly, along with CD4, CD195 / CCR5 functions as a major receptor for HIV. Their ligand is the viral glycoprotein gp120.,CKR5, CCR5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5

基因ID

1234

UniProt

P51681

途径

Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size