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VEGFA 抗体 (Isoform 165)

VEGFA 适用: 人 WB, EIA 宿主: 小鼠 Monoclonal 7G7 unconjugated
产品编号 ABIN155175
发货至: 中国
  • 抗原 See all VEGFA 抗体
    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
    抗原表位
    • 19
    • 15
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    Isoform 165
    适用
    • 146
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    • 73
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    • 1
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    宿主
    • 178
    • 55
    • 12
    • 2
    • 1
    小鼠
    克隆类型
    • 190
    • 57
    • 1
    单克隆
    标记
    • 121
    • 37
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    • 9
    • 3
    • 3
    • 3
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    This VEGFA antibody is un-conjugated
    应用范围
    • 185
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    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    The antibody recognizes human VEGF-A. Other species not tested.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Protein G Chromatography.
    免疫原
    Recombinant Human VEGF165 protein (45 kDa)
    克隆位点
    7G7
    亚型
    IgG1
    Top Product
    Discover our top product VEGFA Primary Antibody
  • 应用备注
    ELISA: Use at 1-15 μg/mL. Western blot: Use at 1-2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore in sterile water to a concentration of 1.0 mg/mL.
    缓冲液
    PBS, pH 7.4 without preservative or stabilizer.
    储存液
    Without preservative
    储存条件
    4 °C
    储存方法
    The lyophilized antibody, thought stable at room temperature, is best stored desiccated below 0 °C. Reconstituted anti-VEGF-A is stable at 4 °C for six weeks or can be stored in working aliquots at - 20 °C for longer.
  • 抗原
    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
    别名
    VEGF-A (VEGFA 产品)
    背景
    VEGFA is a member of the PDGF/VEGF growth factor family and is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternate transcriptional splice variants, encoding either freely secreted or cell associated isoforms, have been characterized. There is also evidence for the use of non AUG (CUG) translation initiation sites upstream of, and in frame with the first AUG, leading to additional isoforms.Synonyms: VEGF, VEGFA, VPF, Vascular endothelial growth factor A, Vascular permeability factor
    基因ID
    7422
    NCBI登录号
    NP_001020537
    UniProt
    P15692
    途径
    RTK signaling, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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