CD34 抗体
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- 抗原 See all CD34 抗体
- CD34
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD34 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This antibody reacts with CD34 - expressed on lymphoid and myeloid hematopoietic progenitor cells. Also reacts with vascular endothelial cells in normal tissues and in benign and malignant proliferations.
- 交叉反应 (详细)
- Species reactivity (tested):Human.
- 纯化方法
- Protein G Chromatography
- 免疫原
- Recombinant Human CD34 protein.
- 克隆位点
- 34C02
- 亚型
- IgG1
- Top Product
- Discover our top product CD34 Primary Antibody
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- 应用备注
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Flow Cytometry. Immunohistology on Frozen Material.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 溶解方式
- Restore in sterile Water to a concentration of 1.0 mg/mL.
- 缓冲液
- 10 mM PBS, pH 7.4 without preservatives or stabilizers
- 储存液
- Without preservative
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- The lyophilized antibody, though stable at RT, is best stored desiccated below 0 °C. Reconstituted antibody is stable at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- CD34
- 别名
- CD34 (CD34 产品)
- 别名
- AU040960 antibody, CD34 molecule antibody, CD34 antigen antibody, CD34 antibody, Cd34 antibody
- 背景
- The highly glycosylated 75-120 kD antigen CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C, suggesting a putative role in signal transduction. Two isoforms of CD34 have been reported to be generated by alternative splicing. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells, brain, and testis. Staining for CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence. CD34, a single chain transmembrane glycoprotein, is selectively expressed on human lymphoid and myeloid hematopoietic progenitor cells.Synonyms: Hematopoietic progenitor cell antigen CD34, Hematopoietic progenitor cell marker
- 基因ID
- 947
- NCBI登录号
- NP_001020280
- UniProt
- P28906
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