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PDK3 抗体

PDK3 适用: 人 WB 宿主: 小鼠 Monoclonal 431CT6-1 unconjugated
产品编号 ABIN1539888
发货至: 中国
  • 抗原 See all PDK3 抗体
    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
    适用
    • 31
    • 30
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    宿主
    • 50
    • 2
    小鼠
    克隆类型
    • 50
    • 2
    单克隆
    标记
    • 29
    • 6
    • 5
    • 4
    • 4
    • 4
    This PDK3 antibody is un-conjugated
    应用范围
    • 45
    • 35
    • 21
    • 3
    • 2
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    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
    免疫原
    Purified His-tagged PDK3 protein(Fragment) was used to produced this monoclonal antibody.
    克隆位点
    431CT6-1
    亚型
    IgG2b
    Top Product
    Discover our top product PDK3 Primary Antibody
  • 应用备注
    WB: 1:100~800
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    PDK3 Antibody(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    有效期
    6 months
  • 抗原
    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
    别名
    PDK3 (PDK3 产品)
    别名
    pdk3 antibody, PDK3 antibody, 2610001M10Rik antibody, AI035637 antibody, zgc:158702 antibody, pyruvate dehydrogenase kinase 3 antibody, pyruvate dehydrogenase kinase, isozyme 3a antibody, pyruvate dehydrogenase kinase, isoenzyme 3 antibody, fragile site, 5-azacytidine type, common, fra(1)(q12) antibody, pyruvate dehydrogenase kinase, isozyme 3b antibody, PDK3 antibody, Pdk3 antibody, pdk3a antibody, pdk3 antibody, FRA1J antibody, pdk3b antibody
    背景
    The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    分子量
    46939
    基因ID
    5165
    NCBI登录号
    NP_001135858, NP_005382
    UniProt
    Q15120
    途径
    PI3K-Akt Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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