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- 抗原 See all TOPBP1 抗体
- TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))
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抗原表位
- pSer1159
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TOPBP1 antibody is un-conjugated
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应用范围
- Dot Blot (DB)
- 预测反应
- M
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This TOPBP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1159 of human TOPBP1.
- 克隆位点
- RB36342
- 亚型
- Ig Fraction
- Top Product
- Discover our top product TOPBP1 Primary Antibody
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- 应用备注
- DB: 1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Phospho-TOPBP1-S1159 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the Phospho-TOPBP1-S1159 Antibody at -20 °C.
- 有效期
- 6 months
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Akt switches TopBP1 function from checkpoint activation to transcriptional regulation through phosphoserine binding-mediated oligomerization." in: Molecular and cellular biology, Vol. 33, Issue 23, pp. 4685-700, (2013) (PubMed).
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Akt switches TopBP1 function from checkpoint activation to transcriptional regulation through phosphoserine binding-mediated oligomerization." in: Molecular and cellular biology, Vol. 33, Issue 23, pp. 4685-700, (2013) (PubMed).
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- 抗原
- TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))
- 别名
- TOPBP1 (TOPBP1 产品)
- 别名
- RGD1562949 antibody, TOPBP1 antibody, cut5 antibody, F2P24.3 antibody, F2P24_3 antibody, meiosis defective 1 antibody, TOP2BP1 antibody, 1110031N14Rik antibody, 2810429C13Rik antibody, AI256758 antibody, D430026L04Rik antibody, mKIAA0259 antibody, TopBP1-A antibody, TopBP1-B antibody, Xmus101 antibody, XtopBP antibody, mus101 antibody, top2bp1 antibody, DNA topoisomerase II binding protein 1 antibody, topoisomerase (DNA) II binding protein 1 antibody, dna topoisomerase ii binding protein 1 (IC) antibody, transcription coactivator antibody, DNA topoisomerase II binding protein 1 L homeolog antibody, Topbp1 antibody, topbp1 antibody, TOPBP1 antibody, MEI1 antibody, topbp1.L antibody
- 背景
- This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.
- 分子量
- 170679
- 基因ID
- 11073
- NCBI登录号
- NP_008958
- UniProt
- Q92547
- 途径
- Chromatin Binding
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