This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This KCNJ18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 amino acids from the N-terminal region of human KCNJ18.
Inwardly rectifying potassium channels, such as KCNJ18, maintain resting membrane potential in excitable cells and aid in repolarization of cells following depolarization. KCNJ18 is primarily expressed in skeletal muscle and is transcriptionally regulated by thyroid hormone (Ryan et al., 2010 [PubMed 20074522]).