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EFCAB4B 抗体 (N-Term)

EFCAB4B 适用: 人 WB 宿主: 兔 Polyclonal RB38227 unconjugated
产品编号 ABIN1539404
发货至: 中国
  • 抗原 See all EFCAB4B 抗体
    EFCAB4B (EF-Hand Calcium Binding Domain 4B (EFCAB4B))
    抗原表位
    • 7
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 48-74, N-Term
    适用
    • 23
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 21
    • 2
    克隆类型
    • 23
    多克隆
    标记
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This EFCAB4B antibody is un-conjugated
    应用范围
    • 23
    • 13
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This EFCAB4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-74 amino acids from the N-terminal region of human EFCAB4B.
    克隆位点
    RB38227
    亚型
    Ig Fraction
    Top Product
    Discover our top product EFCAB4B Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    EFCAB4B Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    有效期
    6 months
  • 抗原
    EFCAB4B (EF-Hand Calcium Binding Domain 4B (EFCAB4B))
    别名
    EFCAB4B (EFCAB4B 产品)
    别名
    CRACR2A antibody, Gm1073 antibody, Gm462 antibody, calcium release activated channel regulator 2A antibody, CRACR2A antibody, Cracr2a antibody
    背景
    Ca(2+)-binding protein that plays a key role in store-operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca(2+) concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca(2+) resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex.
    分子量
    45592
    基因ID
    84766
    NCBI登录号
    NP_001138430, NP_116069
    UniProt
    Q9BSW2
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