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- 抗原 See all CLCF1 抗体
- CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
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抗原表位
- AA 46-72, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CLCF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- M
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This CLCF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-72 amino acids from the N-terminal region of human CLCF1.
- 克隆位点
- RB38733
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CLCF1 Primary Antibody
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anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 88-190) antibody
CLCF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 171-220) antibodyCLCF1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 28-225) antibodyCLCF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 28-178) antibodyCLCF1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) antibodyCLCF1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 29-225) antibodyCLCF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7E10 unconjugated
anti-Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 1-225) antibodyCLCF1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- CLCF1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- 有效期
- 6 months
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- 抗原
- CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
- 别名
- CLCF1 (CLCF1 产品)
- 别名
- clc antibody, nr6 antibody, bsf3 antibody, nnt1 antibody, ciss2 antibody, CLCF1 antibody, BSF-3 antibody, BSF3 antibody, CISS2 antibody, CLC antibody, NNT-1 antibody, NNT1 antibody, NR6 antibody, Bsf3 antibody, Clc antibody, cardiotrophin like cytokine factor 1 antibody, cardiotrophin-like cytokine factor 1 antibody, clcf1 antibody, CLCF1 antibody, Clcf1 antibody
- 背景
- This gene is a member of the glycoprotein (gp)130 cytokine family and encodes cardiotrophin-like cytokine factor 1 (CLCF1). CLCF1 forms a heterodimer complex with cytokine receptor-like factor 1 (CRLF1). This dimer competes with ciliary neurotrophic factor (CNTF) for binding to the ciliary neurotrophic factor receptor (CNTFR) complex, and activates the Jak-STAT signaling cascade. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. CLCF1 is a potent neurotrophic factor, B-cell stimulatory agent and neuroendocrine modulator of pituitary corticotroph function. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- 分子量
- 25176
- 基因ID
- 23529
- NCBI登录号
- NP_001159684, NP_037378
- UniProt
- Q9UBD9
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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