This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This SCRIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 382-410 amino acids from the N-terminal region of human SCRIB.
SCRIB is a cytoplasmic multimodular scaffold protein targeted to epithelial adherens junctions and neuronal presynaptic compartments. SCRIB and its orthologs in vertebrates and invertebrates participate in cell polarization (summary by Nola et al., 2008 [PubMed 18716323]).