This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This LPHN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-397 amino acids from the N-terminal region of human LPHN3.
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane.