This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This GTF2I antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-310 amino acids from the N-terminal region of human GTF2I.
BAP135 antibody, BTKAP1 antibody, DIWS antibody, GTFII-I antibody, IB291 antibody, SPIN antibody, TFII-I antibody, WBS antibody, WBSCR6 antibody, Gtf2ird1 antibody, 6030441I21Rik antibody, BAP-135 antibody, GtfII-I antibody, Spin antibody, bap-135 antibody, bap135 antibody, btkap1 antibody, diws antibody, gtfii-i antibody, ib291 antibody, spin antibody, tfii-i antibody, wbs antibody, wbscr6 antibody, gtf2i antibody, gtf2i.L antibody, general transcription factor IIi antibody, general transcription factor II I antibody, general transcription factor IIi S homeolog antibody, GTF2I antibody, Gtf2i antibody, gtf2i antibody, gtf2i.S antibody
背景
This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7, 13 and 21.