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ITPK1 抗体 (N-Term)

ITPK1 适用: 人 WB 宿主: 兔 Polyclonal RB38858 unconjugated
产品编号 ABIN1539261
发货至: 中国
  • 抗原 See all ITPK1 抗体
    ITPK1 (Inositol-Tetrakisphosphate 1-Kinase (ITPK1))
    抗原表位
    • 15
    • 13
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-54, N-Term
    适用
    • 48
    • 25
    • 20
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 44
    • 4
    克隆类型
    • 46
    • 2
    多克隆
    标记
    • 24
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITPK1 antibody is un-conjugated
    应用范围
    • 48
    • 22
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    B, M
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This ITPK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-54 amino acids from the N-terminal region of human ITPK1.
    克隆位点
    RB38858
    亚型
    Ig Fraction
    Top Product
    Discover our top product ITPK1 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    ITPK1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    有效期
    6 months
  • 抗原
    ITPK1 (Inositol-Tetrakisphosphate 1-Kinase (ITPK1))
    别名
    ITPK1 (ITPK1 产品)
    别名
    ITRPK1 antibody, BC031182 antibody, wu:fj15d08 antibody, zgc:56075 antibody, inositol-tetrakisphosphate 1-kinase antibody, inositol 1,3,4-triphosphate 5/6 kinase antibody, inositol-tetrakisphosphate 1-kinase L homeolog antibody, inositol-tetrakisphosphate 1-kinase a antibody, ITPK1 antibody, Itpk1 antibody, itpk1.L antibody, itpk1a antibody
    背景
    Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconverts the inositol tetraphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. Probably acts as the rate-limiting enzyme of the InsP6 pathway. Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain.
    分子量
    45621
    基因ID
    3705
    NCBI登录号
    NP_001136065, NP_001136066, NP_055031
    UniProt
    Q13572
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