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DMPK 抗体 (N-Term)

DMPK 适用: 人 WB 宿主: 兔 Polyclonal RB36813 unconjugated
产品编号 ABIN1538919
发货至: 中国
  • 抗原 See all DMPK 抗体
    DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))
    抗原表位
    • 15
    • 7
    • 7
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 11-39, N-Term
    适用
    • 40
    • 21
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 52
    • 5
    克隆类型
    • 54
    • 3
    多克隆
    标记
    • 23
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DMPK antibody is un-conjugated
    应用范围
    • 30
    • 25
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This DMPK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-39 amino acids from the N-terminal region of human DMPK.
    克隆位点
    RB36813
    亚型
    Ig Fraction
    Top Product
    Discover our top product DMPK Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    DMPK Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    有效期
    6 months
  • 抗原
    DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))
    别名
    DMPK (DMPK 产品)
    别名
    DMPK antibody, DM antibody, DM1 antibody, DM1PK antibody, DMK antibody, MDPK antibody, MT-PK antibody, Dm15 antibody, DM1 protein kinase antibody, dystrophia myotonica-protein kinase antibody, DMPK antibody, Dmpk antibody
    背景
    The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
    分子量
    69385
    基因ID
    1760
    NCBI登录号
    NP_001075029, NP_001075031, NP_001075032, NP_004400
    UniProt
    Q09013
    途径
    Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development
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