This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This HIST1H2BD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST1H2BD.
HIST1H2BI antibody, H2B.1B antibody, H2B/b antibody, H2BFB antibody, HIRIP2 antibody, dJ221C16.6 antibody, histone cluster 1, H2bd antibody, histone cluster 1 H2B family member d antibody, HIST1H2BD antibody
背景
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Two transcripts that encode the same protein have been identified for this gene, which is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq].