This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This GINS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the Central region of human GINS2.
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背景
The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4, MIM 610611), Psf1 (GINS1, MIM 610608), Psf2, and Psf3 (GINS3, MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.