This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This PRDM10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 744-772 amino acids from the Central region of human PRDM10.
The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.