This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This SSX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-80 amino acids from the Central region of human SSX3.
CT5.3 antibody, SSX2 antibody, SSX3 antibody, SSX family member 3 antibody, protein SSX2 antibody, SSX3 antibody, LOC741661 antibody
背景
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene.