This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This TBC1D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-465 amino acids from the Central region of human TBC1D2.
TBC1D2 acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivativation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.