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- 抗原 See all ATXN7 抗体
- ATXN7 (Ataxin 7 (ATXN7))
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抗原表位
- AA 354-381
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATXN7 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- M
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This ATXN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 354-381 amino acids from the Central region of human ATXN7.
- 克隆位点
- RB36286
- 亚型
- Ig Fraction
- Top Product
- Discover our top product ATXN7 Primary Antibody
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anti-Ataxin 7 (ATXN7) (AA 402-503) antibody
ATXN7 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 7 (ATXN7) (Internal Region) antibodyATXN7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 7 (ATXN7) antibodyATXN7 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 7 (ATXN7) (AA 359-408) antibodyATXN7 适用: 人, 小鼠, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 7 (ATXN7) (Middle Region) antibodyATXN7 适用: 人, 小鼠, 大鼠, 犬, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 7 (ATXN7) (Middle Region) antibodyATXN7 适用: 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- ATXN7 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- 有效期
- 6 months
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- 抗原
- ATXN7 (Ataxin 7 (ATXN7))
- 别名
- ATXN7 (ATXN7 产品)
- 别名
- MGC82940 antibody, ADCAII antibody, OPCA3 antibody, SCA7 antibody, A430107N12Rik antibody, AI627028 antibody, Sca7 antibody, ataxin-7 antibody, RGD1562692 antibody, ataxin 7 L homeolog antibody, ataxin 7 antibody, atxn7.L antibody, atxn7 antibody, ATXN7 antibody, Atxn7 antibody
- 背景
- The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the 'pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. This locus has been mapped to chromosome 3, and it has been determined that the diseased allele associated with spinocerebellar ataxia-7 contains 38-130 CAG repeats (near the N-terminus), compared to 7-17 in the normal allele. The encoded protein is a component of the SPT3/TAF9/GCN5 acetyltransferase (STAGA) and TBP-free TAF-containing (TFTC) chromatin remodeling complexes, and it thus plays a role in transcriptional regulation. Alternative splicing results in multiple transcript variants.
- 分子量
- 95451
- 基因ID
- 6314
- NCBI登录号
- NP_000324, NP_001121621, NP_001170858
- UniProt
- O15265
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