This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This AMPD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-356 amino acids from the Central region of human AMPD3.
AMPD3 is a member of the AMP deaminase gene family. This protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. The protein is the erythrocyte (E) isoforms, whereas other family members isoforms predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency.