This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This PKNOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-324 amino acids from the Central region of human PKNOX2.
Homeodomain proteins are sequence-specific transcription factors that share a highly conserved DNA-binding domain and play fundamental roles in cell proliferation, differentiation, and death. PKNOX2 belongs to the TALE (3-amino acid loop extension) class of homeodomain proteins characterized by a 3-amino acid extension between alpha helices 1 and 2 within the homeodomain (Imoto et al., 2001 [PubMed 11549286]).