This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This ALG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-282 amino acids from the Central region of human ALG2.
This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants.