This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This HRH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-256 amino acids from the Central region of human HRH4.
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene.