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APC 抗体 (AA 1148-1176)

This anti-APC antibody is a 兔 多克隆 antibody detecting APC in WB. Suitable for 小鼠.
产品编号 ABIN1537771
发货至: 中国

Quick Overview for APC 抗体 (AA 1148-1176) (ABIN1537771)

抗原

See all APC 抗体
APC (Adenomatous Polyposis Coli (APC))

适用

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小鼠

宿主

  • 101
  • 19
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克隆类型

  • 91
  • 35
多克隆

标记

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This APC antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB37442
  • 抗原表位

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    AA 1148-1176

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This APC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1148-1176 amino acids from the Central region of human APC.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    APC Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • 抗原

    APC (Adenomatous Polyposis Coli (APC))

    别名

    APC

    背景

    This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

    分子量

    311646

    基因ID

    324

    NCBI登录号

    NP_000029, NP_001120982

    UniProt

    P25054

    途径

    WNT signaling, Stem Cell Maintenance, Cell-Cell Junction Organization
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