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MC1 Receptor 抗体 (AA 205-232)

MC1R 适用: 人 WB 宿主: 小鼠 Monoclonal 578CT6-2-3 unconjugated
产品编号 ABIN1537697
发货至: 中国
  • 抗原 See all MC1 Receptor (MC1R) 抗体
    MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))
    抗原表位
    • 16
    • 15
    • 11
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 205-232
    适用
    • 63
    • 27
    • 11
    • 4
    • 3
    • 1
    • 1
    宿主
    • 66
    • 9
    小鼠
    克隆类型
    • 73
    • 2
    单克隆
    标记
    • 28
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MC1 Receptor antibody is un-conjugated
    应用范围
    • 51
    • 27
    • 26
    • 26
    • 14
    • 12
    • 8
    • 8
    • 6
    • 4
    • 2
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
    免疫原
    This MC1R antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 205-232 amino acids from the Central region of human MC1R.
    克隆位点
    578CT6-2-3
    亚型
    IgM
    Top Product
    Discover our top product MC1R Primary Antibody
  • 应用备注
    WB: 1:100~250
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    MC1R Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    有效期
    6 months
  • 抗原
    MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))
    别名
    MC1R (MC1R 产品)
    别名
    CMM5 antibody, MSH-R antibody, SHEP2 antibody, Mshra antibody, Tob antibody, e antibody, MC1-R antibody, MSHR antibody, mc1r antibody, MC1R antibody, TUBB3 antibody, melanocortin 1 receptor antibody, melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) antibody, MC1R antibody, Mc1r antibody, mc1r antibody, mc1r_par1 antibody
    背景
    This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation. [provided by RefSeq].
    分子量
    34706
    基因ID
    4157
    NCBI登录号
    NP_002377
    UniProt
    Q01726
    途径
    cAMP Metabolic Process, Feeding Behaviour
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