This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This UBA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 861-889 amino acids from the C-terminal region of human UBA6.
Modification of proteins with ubiquitin (UBB, MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed 17597759]).