This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This TBC1D10B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 781-808 amino acids from the C-terminal region of human TBC1D10B.
TBC1D10B antibody, EPI64B antibody, 1110003P22Rik antibody, C87963 antibody, RGD1309191 antibody, TBC1 domain family member 10B antibody, TBC1 domain family, member 10b antibody, TBC1D10B antibody, Tbc1d10b antibody
背景
Small G proteins of the RAB family (see MIM 179508) function in intracellular vesicle trafficking by switching from the GTP-bound state to the GDP-bound state with the assistance of guanine nucleotide exchange factors (GEFs, see MIM 609700) and GTPase-activating proteins (GAPs). TBC1D10B functions as a GAP for several proteins of the Rab family (Ishibashi et al., 2009 [PubMed 19077034]).