This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This MUM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 671-699 amino acids from the C-terminal region of human MUM1.
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.