This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This SIGLEC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 667-695 amino acids from the C-terminal region of human SIGLEC10.
SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6 (MIM 604405).