This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This ELMO3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 594-622 amino acids from the C-terminal region of human ELMO3.
The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes.