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SOCS7 抗体 (C-Term)

SOCS7 适用: 人 WB 宿主: 兔 Polyclonal RB37084 unconjugated
产品编号 ABIN1537362
发货至: 中国
  • 抗原 See all SOCS7 抗体
    SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))
    抗原表位
    • 15
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 458-486, C-Term
    适用
    • 42
    • 20
    • 19
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 41
    • 1
    克隆类型
    • 41
    • 1
    多克隆
    标记
    • 13
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SOCS7 antibody is un-conjugated
    应用范围
    • 31
    • 18
    • 13
    • 13
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    M
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This SOCS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-486 amino acids from the C-terminal region of human SOCS7.
    克隆位点
    RB37084
    亚型
    Ig Fraction
    Top Product
    Discover our top product SOCS7 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    SOCS7 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    有效期
    6 months
  • 抗原
    SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))
    别名
    SOCS7 (SOCS7 产品)
    背景
    Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
    分子量
    62969
    基因ID
    30837
    NCBI登录号
    NP_055413
    UniProt
    O14512
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