LKB1 抗体 (C-Term)
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- 抗原 See all LKB1 (STK11) 抗体
- LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
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抗原表位
- AA 387-417, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LKB1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This STK11 (LKB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-417 amino acids from the C-terminal region of human STK11 (LKB1).
- 克隆位点
- RB3549-3550
- 亚型
- Ig Fraction
- Top Product
- Discover our top product STK11 Primary Antibody
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- 应用备注
- IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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A novel LKB1 isoform enhances AMPK metabolic activity and displays oncogenic properties." in: Oncogene, Vol. 34, Issue 18, pp. 2337-46, (2015) (PubMed).
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A novel LKB1 isoform enhances AMPK metabolic activity and displays oncogenic properties." in: Oncogene, Vol. 34, Issue 18, pp. 2337-46, (2015) (PubMed).
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- 抗原
- LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
- 别名
- STK11 (LKB1) (STK11 产品)
- 背景
- STK11, is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.
- 分子量
- 48636
- 基因ID
- 6794
- NCBI登录号
- NP_000446
- UniProt
- Q15831
- 途径
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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