This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This UBE2Z antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-310 amino acids from the C-terminal region of human UBE2Z.
Modification of proteins with ubiquitin (UBB, MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE2Z is an E2 enzyme (Jin et al., 2007 [PubMed 17597759]).[supplied by OMIM].