This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This KCTD13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-258 amino acids from the C-terminal region of human KCTD13.
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration.