This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This HOXB13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-251 amino acids from the C-terminal region of human HOXB13.
This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region.